Objective To compare the diagnostic value between two-dimensional shear wave elastography (2D-SWE) and transient elastography (TE) for the stage liver fibrosis in patients with chronic hepatitis B (CHB).Methods One hundred and forty-eight cases of CHB patients performed 2D-SWE and TE examinations. The pathological fibrosis stage by ultrasound guided liver biopsy was used as the reference standard to evaluate the diagnostic efficacy of two kinds of elastography. Results There are positive interrelationships between two kinds of elastography and liver fibrosis(r =0.914、0.783).There were significant differences between 2D-SWE and TE quantitative elasticity in different pathological fibrosis stage(P ＜0.05), and the value of elasticity increased with the stage of liver fibrosis. The receiver operating characteristic curve (ROC curve) was used to compare the diagnostic efficacy between 2D-SWE and TE. The areas under the ROC curve(AUC) of 2D-SWE diagnosis of liver fibrosis (S2～S4) were 0.972,0.973 and 0.976,The AUC of TE diagnosis of liver fibrosis were 0.903、0.909 and 0.904,and there were significant differences that 2D-SWE was superior than TE in each liver fibrosis（S2:Z =3.062，S3:Z =3.379，S4:Z =2.539，all P ＜0.05).Conclusion 2D-SWE and TE have similar diagnostic value in noninvasive diagnosis of liver fibrosis with CHB, but the 2D-SWE which has more clinical application value is superior to TE.