摘要: |
目的: 探讨超声左心室压力-应变环(PSL)技术评价甲状腺功能减退患者左心室心肌做功的价值。方法: 连续纳入四川省人民医院就诊的甲状腺功能减退患者42例作为甲减组,同时选取健康志愿者44例作为对照组。采集二维超声数据并使用PSL技术获得心肌整体纵向应变(GLS)、整体有用功 (GCW)、整体无用功(GWW)、做功指数(GWI)、整体做功效率 (GWE),手动计算心肌基底段、中间段和心尖段的做功指数(MWI)、做功效率(MWE)、有用功(CW)、无用功(WW)的平均值。比较两组相关参数的差异。结果: ①常规超声心动图参数:与对照组相比,甲减组舒张末期室间隔厚度(IVSd)和舒张末期左心室后壁厚度(LVPWd)较高,舒张早期二尖瓣口E峰峰值血流速度(E)、舒张晚期二尖瓣口A峰峰值血流速度(A)、舒张早期左心室侧壁二尖瓣环运动峰值速度(e')和E/A均较低(均P<0.05)。 ②左心室整体心肌做功参数:与对照组相比,甲减组GWW增高,GLS、GWI、GCW、GWE均降低(均P<0.05)。③左心室各节段心肌做功参数:与对照组相比,甲减组基底段、中间段和心尖段MWI、CW和MWE均降低, WW增高(均P<0.05)。 结论: PSL技术能够定量评估甲减患者心肌做功,为患者的后续疾病进展和疗效判断提供准确影像学依据。 |
关键词: 超声心动描记术 甲状腺功能减退 左心室 压力-应变环 心肌做功 |
DOI: |
投稿时间:2022-12-04修订日期:2023-02-02 |
基金项目:国家重点研发计划项目 (2020YFC2008000) ;中央高校基本科研业务基金 (ZYGX2020ZB038);国家自然科学基金 (81671852) |
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Assessment of left ventricular myocardial work in patients with hypothyroidism by ultrasonic non-invasive pressure-strain loopPENG Yi1,YIN Lixue2,ZHANG Li3,WANG Rui2,ZHU Hao2 |
pengyi,yinlixue,zhangli,wangrui,zhuhao |
() |
Abstract: |
Objective: To explore the value of ultrasonic left ventricular pressure-strain loop (PSL) for evaluating left ventricular myocardial work in patients with hypothyroidism. Methods: A total of 42 patients with hypothyroidism treated in Sichuan Provincial People's Hospital were included as the hypothyroidism group , and 44 healthy volunteers were also employed as the control group. Collect two-dimensional ultrasonic data and use the left ventricular PSL technology to obtain the myocardial global longitudinal strain (GLS) , global work index (GWI), global constructive work (GCW), global wasted work (GWW) and global work efficiency (GWE) , and manually calculate the average values of myocardial work index (MWI) , myocardial work efficiency (MWE), constructive work (CW), and wasted work (WW) of basal, middle and apical segments of myocardium. The differences in relevant parameters between the two groups were compared. Results: ①Routine echocardiographic parameters: compared with the control group , interventricular septal thickness at end-diastole (IVSd) and left ventricular posterior wall thickness at end-diastole (LVPWd) were larger, and early diastolic E peak blood flow (E)、late diastolic A peak blood flow (A) at mitral valve orifice、early diastolic mitral annular peak velocity(e') of left ventricular lateral wall and E/A were lower in the hypothyroidism group (all P < 0.05).②Left ventricular global myocardial work parameters: compared with the control group, GWW was higher and GLS , GWI , GCW and GWE were lower in the hypothyroidism group (all P < 0.05).③Myocardial work parameters of each segment of left ventricle: compared with the control group , MWI , CW and MWE of basal segment , middle segment and apical segment in the hypothyroidism group were lower , while WW were larger (all P<0.05). Conclusion: PSL technique could be used to quantitatively assess myocardial work in patients with hypothyroidism for providing accurate imaging evidences for the early diagnosis and efficiency evaluation of hypothyroidism patients treatment . |
Key words: Echocardiography Hypothyroidism Left ventricle Pressure–strain loop Myocardial work |