摘要: |
目的 分析超微血流成像(Superb microvascular imaging, SMI)半定量分级在前列腺癌检出中的应用价值。材料与方法 筛选129例经病理确诊的前列腺疾病患者,以穿刺活检组织病理作为诊断金标准,将前列腺增生及前列腺炎等良性疾病纳入良性组,共40例;将前列腺腺泡腺癌纳入恶性组,共89例。依据灰阶超声及SMI共同检出的可疑病灶作为SMI半定量分析评价靶区。参照Adler血流分级及滑膜半定量评分系统的血流占比评价方式,将病灶内部微细血流行半定量分级,0级:病灶内未见微细血流;I级:病灶内探及稀疏1-2个点状血流信号;II级:病灶内部探及3-4条短线状血流、分布占比不超过病灶最大截面50%;III级:病灶内探及4条以上血流、分布占比超过病灶截面50%。结果 良性组中SMI0级7例、1级9例、2级12例、3级12例,恶性组中SMI1级2例、SMI2级10例、SMI3级77例。良性组中SMI表现各异,而恶性组中SMI3级为77例,占比高达86.5%。SMI对前列腺癌的诊断敏感性、特异性、阳性预测值、阴性预测值、准确率分别为86.51%、70.00%、86.51%、70.00%、81.39%。结论 在结合二维超声的基础上,SMI半定量分级在鉴别前列腺良恶性肿瘤上有一定应用价值,可联合血PSA用于前列腺癌的早期筛查中。 |
关键词: 前列腺癌 超微血流成像 SMI 超声检查 |
DOI: |
投稿时间:2020-10-21修订日期:2020-11-26 |
基金项目:国家自然科学基金项目(面上项目,重点项目,重大项目),基于智能型诊疗一体化探针靶向乳腺癌超声/光声双模态显像及可视化精准治疗 |
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The application of semi-quantitative classification of Superb microvascular imagingin the detection of prostate cancer |
Hong Ruixia,Li Fang,Zhou Hang,Ran Haitao |
(1.Chongqing Medical University;China) |
Abstract: |
Object To analyze the application value of Superb microvascular imaging (SMI) semi-quantitative classification in the detection of prostate cancer. Materials and methods Screened 129 patients with prostate disease diagnosed pathologically, and took biopsy histopathology as the diagnostic gold standard. Benign diseases such as prostatic hyperplasia and prostatitis were included in the benign group, a total of 40 cases; prostate acinar adenocarcinoma was included in the malignant group, a total of 89 example. Suspicious lesions detected by gray-scale ultrasound and SMI are used as evaluation target areas of the SMI semi-quantitative analysis. Refer to Adler blood flow grading and synovial semi-quantitative scoring system of the evaluation the proportion of blood flow to semi-quantitatively classify the prevalence of fine blood within the lesion. Grade 0: No fine blood flow in the lesion; Grade I: Probe 1 -2 sparse punctate blood flow signal within the lesion ; Level II: 3-4 short-line blood flows within the lesion, and the distribution does not exceed 50% of the maximum cross-section of the lesion; Level III: Detection within the lesion and more than 4 blood flows and distribution It accounts for more than 50% of the cross-section of the lesion. Results In the benign group, there were 7 cases of SMI grade 0, 9 cases of grade 1, 12 cases of grade 2, and 12 cases of grade 3. In the malignant group, there were 2 cases of SMI grade 1, 10 cases of SMI grade 2 and 77 cases of SMI grade 3. The performance of SMI in the benign group was different, while in the malignant group, there were 77 cases of SMI grade 3, accounting for 86.5%. The diagnostic sensitivity, specificity, positive predictive value, negative predictive value and accuracy of SMI for prostate cancer were 86.51%, 70.00%, 86.51%, 70.00%, and 81.39%, respectively.Conclusion Based on the combination of two-dimensional ultrasound, SMI semi-quantitative classification has certain application value in the identification of benign and malignant prostate tumors. It can be combined with blood PSA for early screening of prostate cancer. |
Key words: Prostate cancer Superb microvascular imaging SMI Ultrasonography |